[HTML][HTML] Recent developments in the treatment of Parkinson's Disease

TB Stoker, RA Barker - F1000Research, 2020 - ncbi.nlm.nih.gov
Parkinson’s disease (PD) is a common neurodegenerative disease typified by a movement
disorder consisting of bradykinesia, rest tremor, rigidity, and postural instability. Treatment …

[HTML][HTML] Emerging therapeutic strategies for Parkinson's disease and future prospects: a 2021 update

NA Gouda, A Elkamhawy, J Cho - Biomedicines, 2022 - mdpi.com
Parkinson’s disease (PD) is a neurodegenerative disorder pathologically distinguished by
degeneration of dopaminergic neurons in the substantia nigra pars compacta. Muscle rigidity, …

[HTML][HTML] Precision medicine in Parkinson's disease: emerging treatments for genetic Parkinson's disease

SA Schneider, RN Alcalay - Journal of neurology, 2020 - Springer
… The lowest carrier frequency was reported to be 2.3% in Norwegian Parkinson's disease
patients [13]. Notably, there is considerable reduction of penetrance in that only about 10% of …

[HTML][HTML] Current therapies in clinical trials of Parkinson's disease: A 2021 update

EM Prasad, SY Hung - Pharmaceuticals, 2021 - mdpi.com
… Food and Drug Administration approved the drug levodopa … identified 47 trials as PD treatment
drugs or therapies. Among them, … Additionally, we discuss the most potent drug or therapy …

Cholinergic system changes in Parkinson's disease: emerging therapeutic approaches

NI Bohnen, AJ Yarnall, RS Weil, E Moro… - The Lancet …, 2022 - thelancet.com
… Our goal is to provide an update of cholinergic systems and changes in Parkinson's disease
and isolated REM sleep behaviour disorder, a Parkinson's disease prodrome. We discuss …

[HTML][HTML] Systematic review on Parkinson's disease medications, emphasizing on three recently approved drugs to control Parkinson's symptoms

P Sivanandy, TC Leey, TC Xiang, TC Ling… - International journal of …, 2021 - mdpi.com
… , the number of patients with Parkinson’s disease in this region is expected to more than
fivefold by 2040, from an estimated 20,000 to 120,000 [15]. Familial Parkinson disease (FPD) is …

Transcription factor EB: an emerging drug target for neurodegenerative disorders

JX Song, J Liu, Y Jiang, ZY Wang, M Li - Drug Discovery Today, 2021 - Elsevier
… ’s disease and Parkinson’s disease. So far, the findings are exciting and promising. Here,
we delineate the dysfunction of the TFEB-mediated ALP in NDs, and we summarize small …

[HTML][HTML] Levodopa-induced dyskinesia in Parkinson's disease: pathogenesis and emerging treatment strategies

DK Kwon, M Kwatra, J Wang, HS Ko - Cells, 2022 - mdpi.com
The most commonly used treatment for Parkinson’s disease (PD) is levodopa, prescribed in
conjunction with carbidopa. Virtually all patients with PD undergo dopamine replacement …

Parkinson's disease: etiopathogenesis and treatment

J Jankovic, EK Tan - Journal of Neurology, Neurosurgery & Psychiatry, 2020 - jnnp.bmj.com
… insights into evidence-based63 as well as emerging and experimental therapeutics of PD. …
. The 200-year journey of Parkinson disease: reflecting on the past and looking towards the …

Parkinson's disease: Current drug therapy and unraveling the prospects of nanoparticles

A Paul, KS Yadav - Journal of Drug Delivery Science and Technology, 2020 - Elsevier
… in medical history for James Parkinson's by addition of more symptoms to … Parkinson's
disease (PD) for those symptoms [4]. Being the second most familiar ND after Alzheimer's disease